LDN-27219 CHEMICAL STRUCTURE - AN OVERVIEW

In distinction to neurodegerative diseases and cancer, the contribution of TG2 activity to celiac sprue pathogenesis is relatively properly proven. The deamidation of distinct glutamine residues targeted by TG2 in gluten peptides is shown to enhance peptide binding to the disease-associated proteins HLA-DQ2/eight, which can be the only known geneti